Purity:Purified by ammonium sulfate precipitation.
Form:Supplied as a liquid in 10mM PBS, pH 7.4. Also available with BSA and azide. See T5100-06B.
Specificity:Blocks anti-angiogenic activity of TSP-1 by inhibiting its binding to TSP-Receptor / CD36. It shows no crossreactivity with fibronectin, fibrinogen and von Willebrand factor. It inhibits the adhesion of human melanoma G361 cells, keratinocytes, squamous carcinoma cells and rat smooth muscle cells to TSP.1 It does not inhibit aggregation of thrombin-induced platelets. Species Crossreactivity: human, mouse, rat, bovine, chicken.
Clone # USB:A4.1
Isotype:IgM
Calc Applications Abbrev:FC IF WB
Calc Crossreactivity:Bo Ch Hu Mo Rt
Immunogen:Calcium-replete, native purified human TSP from the supernatant of thrombin-activated platelets