85-7220-18　c-erbB2 (HER-2, neu Receptor) (BSA & Azide Free) 100ul　C0026-11QX

仕様

• Size：100ul
• Host：mouse
• Source Antibody：human
• Grade：Affinity Purified
• Purity：Purified by Protein G affinity chromatography.
• Form：Supplied as a liquid in PBS, pH 7.4. No stabilizing proteins added. No preservative added. Glycerol free. Also available with BSA. See C0026-11Q.
• Specificity：Recognizes human c-erbB2. Inhibits the binding of EGF and NDF to their direct receptors. Reduces affinity of EGF (3-fold) and NDF (2-fold) for their receptors. Inhibits tumorigenic growth. Demonstrates modest effect on c-erbB-2 internalization. Induces the tyrosine kinase activity of the c-erbB-2. Accelerates dissociation of EGF/NDF from their cellular binding sites. Inhibits mitogenic effect of EGF/NDF. Inhibits dimerization of c-erbB Receptors.
• Clone # USB：3F36
• Isotype：IgG1,k
• Calc Applications Abbrev：IP
• Calc Crossreactivity：Hu
• Immunogen：Recombinant protein corresponding to the extracellular domain of human c-erbB-2/HER-2 oncoprotein. Cellular Localization: Cell membrane; MW of antigen: 185kD; Epitope: Involved in the formation of heterodimers.
• Shelf Life：1year
• EU Commodity Code：30021010
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