85-7220-17　c-erbB2 (HER-2, neu Receptor) 500ul　C0026-11Q

仕様

• Size：500ul
• Host：mouse
• Source Antibody：human
• Grade：Affinity Purified
• Purity：Purified by Protein G affinity chromatography from ascites.
• Form：Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See C0026-11QX.
• Specificity：Recognizes human c-erbB2. Inhibits the binding of EGF and NDF to their direct receptors. Reduces affinity of EGF (3-fold) and NDF (2-fold) for their receptors. Inhibits tumorigenic growth. Demonstrates modest effect on c-erbB-2 internalization. Induces the tyrosine kinase activity of the c-erbB-2. Accelerates dissociation of EGF/NDF from their cellular binding sites. Inhibits mitogenic effect of EGF/NDF. Inhibits dimerization of c-erbB Receptors.
• Clone # USB：3F36 (L26)
• Isotype：IgG1,k
• Calc Applications Abbrev：IP
• Calc Crossreactivity：Hu
• Immunogen：Recombinant protein corresponding to the extracellular domain of human c-erbB-2/HER-2 oncoprotein. Cellular Localization: Cell membrane. Epitope: Involved in the formation of heterodimers.
• Shelf Life：1year
• EU Commodity Code：30021010
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