Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2.
Specificity:Recognizes mouse p53. Recognizes both mutant forms and wild-type human p53 under denaturing conditions. Species crossreactivity: rat, human and most other mammals. Does not cross-react with Xenopus laevis. Detection of p53 using this antibody: 50% of colon cancer sections, 30% of breast cancer sections, and 70% of lung cancer sections are positive.
Clone # USB:3C167 (PAb 240)
Isotype:IgG1,k
Calc Applications Abbrev:E FC IHC IP WB
Calc Crossreactivity:Hu Ma Mo Rt
Immunogen:Gel-purified p53-beta-galactosidase fusion protein containing murine p53 aa14-389 from pSV53C cDNA clone. Epitope: aa213- 217 on human p53. Cellular Localization: nuclear.