Specificity:Recognizes bovine Ubiquitin (76 amino acid, 8.5kD) both conjugated and unconjugated. Shows staining of tangle material in Alzheimer affected brain and also stains other pathological inclusions such as Lewy bodies (in Parkinson’s disease) and Pick bodies (in Pick’s disease). Species Crossreactivity: human, mouse and rat
Clone # USB:Ubi-1 (aka 042691GS)
Isotype:IgG1,k
Calc Applications Abbrev:IHC IP WB
Calc Crossreactivity:Bo Hu Mo Rt
Immunogen:Purified ubiquitin (bovine RBC) covalently coupled to KLH using glutaraldehyde. Species sequence homology: chicken and drosophila