Specificity:Recognizes human Chondroitin 6 Sulfate. Reacts with a wide range of cartilage proteoglycans after either chondroitinase (ABC or AC) or testicular hyaluronidase digestion. Antibody binding to epitope is successfully inhibited by disaccharides of chondroitin-6-sulfate. Recognizes the chondroitin-6-sulfate stubs (preferentially in clusters) of high density cartilage proteoglycans of different species. Does not react with native proteoglycans, dermatan sulfate, keratan sulfate or chondroitin-4-sulfate. Species Crossreactivity: chondroitin-6-sulfate stubs of all proteoglycans of all species.
Clone # USB:2Q551 (MK-302)
Isotype:IgG1
Calc Applications Abbrev:E RIA
Calc Crossreactivity:Bo Ca Hu Mo Rb Rt Sh
Immunogen:Chondroitinase ABC-digested adult human aggrecan.