Form:Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Specificity:Recognizes an oncoprotein of 64–67kD, identified as c-myc. Its epitope spans between aa410–419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. Shows no crossreactivity with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Species Reactivity: Human. Does not react with mouse, rat and chicken.
Clone # USB:9E10.3
Isotype:IgG1,k
Calc Applications Abbrev:FC IF IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide, corresponding to aa408–439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from the C-terminus of human c-myc, coupled to KLH