Purity:Purified ascites. Tested by electrophoresis and Flow Cytometry.
Form:Supplied as a liquid in 0.1M Tris-HCl, 0.5M sodium chloride, 10mM glycine, pH 8.0, 0.2% BSA, 0.09% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Recognizes a glycoprotein of 105kD found on circulating B-lymphocytes. Reacts with HRIK and Raji cell lines. Clinical Expression: B cell prolymphocytic leukemia (B-PLL): strongly positive; Hairy cell leukemia (HCL): strongly positive; Hairy cell leukemia variant (HCL-V): strongly positive; Splenic lymphoma with villous lymphocytes (SLVL): positive; B cell chronic lymphocytic leukemia (B-CLL): negative to weakly positive. No reaction with granulocytes, monocytes, platelets, erythrocytes, T lymphocytes or null cells.
Clone # USB:2Q385 (FMC-7)
Isotype:IgM
Calc Applications Abbrev:FC
Calc Crossreactivity:Hu
Immunogen:The human B-lymphoblastoid cell line, HRIK.