Troponin T is a thin filament regulatory protein of striated muscle that binds to troponin C and I and to tropomyosin and is required for calcium-dependent ATPase activity of myofibrillar proteins.
It is important in proper muscle function and myofibril formation.
In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner.
This expression in the human heart is affected by heart failure.
Applications:Suitable for use in ELISA, Immunoaffinity Purification and Western Blot.
Other applications have not been tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Recommended Pair:Suitable for use as the capture or solid phase antibody.
Matched to T8665-22A, T8665-22B or T8665-30A as the detection or conjugate (label) antibody.
Hybridoma:Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：1mg
Host：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity：Recognizes human cardiac Troponin T. Recognizes an epitope between aa60-70. Does not crossreact with human skeletal Troponin T. Species Crossreactivity: Bovine and chicken. Does not react with canine, feline, fish, porcine, mouse, goat, rabbit or rat.
