85-7210-97　Tetrahydrocannabinol (THC) 1mg　T2970-21

特徴

• Cannabinoids, a group of C21 compounds present in Cannabis sativa L., their carboxylic acids, analogs, and transformation products, are the active ingredients found in hasish and marihuana.
• (-)-trans-D9-tetrahydrocannabinol (D9-THC) is the major psychopharmacologically active component of cannabis.
• Cannabis affect cognition and memory, euphoria and sedation, and antinociception (analgesia) without the respiratory depression problems associated with opioid analgesics.
• D9-THC is also immunosuppressive and impairs cell-mediated immunity, humoral immunity and cellular defenses against a variety of infectious agents both in vivo and in vitro.
• To date, two sub-types of the G-protein coupled cannabinoid receptor, CB1 and CB2, have been identified.
• The first brain-derived endogenous cannabinoids, an unsaturated fatty-acid ethanolamide, arachidonylethanolamide (AEA, also called anandamide) was found in brain.
• AEA has higher affinity for the CB1 than for the CB2.
• THC is rapidly adsorbed by the lungs and almost completely metabolized.
• The major metabolite is 11-nor-delta-9-tetrahydrocannbinol-9-carboxylic acid and is found with other metabolites in plasma, feces, and urine.
• THC-metabolites can be detected within hours or exposure and may be detectable for several days.
• A cut-off level of 50ng/ml marijuana metabolites has been selected as the initial screening level by the US Dept.
• of Health.
• Applications:Suitable for use in EIA and Lateral Flow/Rapid test formats.
• Other applications have not been tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.