Carcinoembryonic Antigen (CEA) is a 180kD tumor-associated cell surface glycoprotein.
CEA is synthesized during development in the fetal gut.
It is re-expressed in increased amounts in intestinal carcinomas and several other tumors.
Anti-CEA is reportedly useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).
Applications:Suitable for use in ELISA, Solid Phase Immobilization, Enzyme Conjugation and Radiolabeling.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Hybridoma:P3X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.
Affinity Constant: 2x10e9
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage, store at -20°C.
Aliquots are stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:1mg
Host:mouse
Source Antibody:human
Grade:Highly Purified
Purity:Purified by DEAE chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Recognizes human Carcinoembryonic Antigen (CEA).