85-7210-33　Myelin Basic Protein, aa130-136 (MBP) 100ug　M9758-01

特徴

• Myelin basic protein (MBP) is a single-chain, flexible polypeptide of ~18.5kD existing in its natural environment as an extrinsic and loosely bound component of the cytoplasmic portion of the myelin membrane sandwich.
• Ultrastructural immunocytochemistry with anti-myelin basic protein has shown that MBP is localized in the compact myelin sheath.
• MBP has not been demonstrated in rough endoplasmic reticulum, lysosomes or any other cytoplasmic organelles.
• MBP serves as a marker for oligodendrocytes and Schwann cells.
• MBP is also a marker for malignant schwannomas and appears to play a significant role in the etiology of multiple sclerosis and experimental autoimmune encephalomyelitis.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and quantification of myelin basic protein.
• Other applications have not been tested.
• Recommended Dilutions:Immunohistochemistry: Frozen or paraffin-ebedded sections
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.