The E antigen is also known as HBeAg or precore antigen.
It is one of two HBV core proteins and is secreted into the serum of infected patients, usually early on in the infection.
Positive testing for HBeAg usually indicates active replication of HBV and is associated with in increased risk of hepatocellular carcinoma.
HBeAg also elicits T cell tolerance and regulates the immune response to the intracellular nucleocapsid of the virus.
This HBeAg-mediated immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Affinity Constant:1x10e9L/mole
Matched Pair:Detection: H1915-08
Capture: H1915-09
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：1mg
Host：mouse
Source Antibody：human
Grade：Highly Purified
Purity：Purified by Caprylic acid. >90% by SPE gel.
Form：Supplied as a liquid in 10mM PBS, pH 7.2 0.02% sodium azide.
Specificity：Recognizes the “e” antigen of human hepatitis B virus.
Clone # USB：1.B.308
Isotype：IgG1
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to HBeAg
