Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2).
CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1.
This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells.
The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines.[CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.1M Tris HCl, pH 7.5.
Specificity：Recognizes recombinant human MIP2 alpha. Crossreacts with recombinant human-MIP2b and recombinant human-MIP-2a (ELISA). Does not crossreact with recombinant human-MIP1a or recombinant human-MIP1b.
Clone # USB：1.A.12
Isotype：IgG2b
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Recombinant human MIP-2a produced in genetically engineered yeast and purified by sequential chromatography.
