85-7208-64　Yersinia pestis discontinued 500ug　Y2052-05

特徴

• Y.
• pestis has a number of virulence factors that enable it to survive in humans by facilitating use of host nutrients, causing damage to host cells, and subverting phagocytosis and other host defense mechanisms.
• Capsular F1 antigen is a main immunochemical component of Y.
• pestis surface.
• Its synthesis is determined by pFra plasmid and induced at 370C.
• F1 is aggregated on the outer membrane of the Y.
• pestis microbe as an olygomeric protein, forming a granular layer and gradually diffusing into the environment.
• Capsular polymer consists of multiple similar hydrophobic protein subunits, aggregating at physiological conditions.
• F1 subunit of the antigen is originally synthesized from 170 amino acids and has a molecular mass 17.6Kd, then, after the elimination of the signal peptide during the secretion onto the surface, a protein with molecular mass 15.6Kd and isoelectric point 4.1 is formed.
• Applications:Suitable for use in Immunohistochemistry and ELISA.
• Other applications not tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.