Keratin 15 is a type I keratin without a defined type II partner.
Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail.
Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars.
Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.
Applications:Suitable for use in Immunofluorescence.
Other applications have not been tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：500ul
Host：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography from ascites.
Form：Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Specificity：Recognizes human keratin 15. Species Crossreactivity: bovine, mouse and rat.
Clone # USB：0.N.360
Isotype：IgG2a,k
Calc Applications Abbrev：IF
Calc Crossreactivity：Bo Hu Mo Rt
Immunogen：Synthetic peptide corresponding to 17 residues from the C-terminal of human cytokeratin 15. Cellular Localization: Cytoplasmic.
