85-7207-48　［取扱停止］CD155, PVR (Polio Virus Receptor) 500ul　C2548-85

特徴

• PVR is a member of Ig-superfamily with 3 Ig-domains in arrangement V-C-C.
• Four mRNAs are produced from single gene for PVR, (mapped to human chromosome band 19q13.1-13.2).
• Two of the mRNAs (called H20A and H20B or alpha and kappa,) encode cell surface molecules of about 43kD and 45kD polypeptide backbone, respectively.
• Two other splice variants, Beta and gamma encode secreted molecules of about 44kD.
• The cytoplasmic tails are short (aa 35-50) and are rich in serine phosphorylated residues.
• C2548-85 protects HeLa cells against the cytopathic effect of all three poliovirus serotypes.
• Intact Ig or Fab fragment of C2548-85 prevents binding of S-labeled poliovirus to HeLa cells.
• Applications:Suitable for use in Flow Cytometry and Immunofluorescence, Inhibition of Replications of Polio virus in HeLa cells use C2548-85X.
• Not suitable for use in Western Blot.
• Other applications have not been tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Positive Control:HeLa, SV80, HE-p2, RD, A431, HL-60, U-937 cells, monkey vero, GMK and TC-7 cells.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.