85-7207-36　［取扱停止］CD38 (Acute Lymphoblastic Leukemia Cells Antigen, ADP Ribosyl Cyclase, CADPr Hydrolase 1, Cyclic ADP Ribose Hydrolase, Ecto Nicotinamide Adenine Dinucleotide Glycohydrolase, I19 (Mouse), Lymphocyte Differentiation Antigen) 500ul　C2390-05

特徴

• CD38 is a single chain type II integral transmembrane protein.
• It is highly expressed on thymocytes.
• It is also present on activated T cells and terminally differentiated B cells (plasma cells).
• Other reactive cells include NK cells, monocytes, macrophages, and dendritic cells.
• CD38 may be detected on cells from multiple myeloma, ALL (B and T) and some AML.
• It is not found on most mature resting peripheral lymphocytes.
• CD38 functions as a multicatalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor.
• Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e.
• identification of myelomas), and as a marker for activated B and T cells.
• Applications:Suitable for use in Immunohistochemistry.
• Not suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilutions:Immunohistochemistry (Formalin/paraffin): 1:50-1:100 for 60 minutes at RT.
• Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 minutes, followed by cooling at RT for 20 minutes.
• Requires use of a high-sensitivity detection system.
• Optimal dilutions to be determined by the researcher.
• Positive Control:Tonsil
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.