CD25, otherwise known as the Tac antigen or p55, is the alpha chain of the Interleukin-2 (IL-2) receptor.
The IL-2 receptor is expressed on activated cells including T cells, B cells and monocytes.
It is also present on a subset of thymocytes, HTLV-1 transformed T and B cells, EBV transformed B cells, myeloid precursors and oligodendrocytes.
IL-2 induces the expression of the CD25 subunit on NK cells.
The IL-2 receptor consists of at least three distinct membrane components: the alpha chain (IL-2R-alpa, Tac, CD25), the beta chain (IL-2R-beta, p75, CD122), and the gamma chain (IL-2R-gamma).
CD25 is undetectable on resting T cells but is induced upon T-cell activation.
Applications:Suitable for use in Flow Cytometry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Positive Control:Tonsil or lymph node.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography from ascites.
Form：Supplied as a liquid in PBS, pH 7.4. Also available with BSA and azide. See C2276-10.
Specificity：Recognizes human interleukin-2 receptor (IL-2Ra).
Clone # USB：0.N.93 (IL2R.1)
Isotype：IgG1,k
Calc Applications Abbrev：FC IF IHC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to human interleukin-2 receptor. Cellular Localization: Cell membrane
