Human Thyroglobulin (Tg) is a 660kD, dimeric protein produced by and used entirely within the thyroid gland.
Human Thyroglobulin Tg was referred to as 'colloid'.
Human Thyroglobulin (Tg) is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine.
Patients with Hashimoto's thyroiditis or Graves' disease, frequently develop antibodies against human Thyroglobulin (Tg).
Human Thyroglobulin Tg-specific antibodies help in the diagnosis of these diseases, but they also may be present in apparently healthy euthyroid individuals.
Human Thyroglobulin (Tg) levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer.
Thyroglobulin (Tg) levels in the blood can also be elevated in cases of Graves disease.
Applications:Suitable for use in ELISA.
Other applications have not been tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Matched Pair:Suitable for use as the capture or solid phase antibody.
Matched to T5300-01 as the detection or conjugate (label) antibody.
Affinity Constant: ~2x10e9 L/mole
Source: Ascites
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：1mg
Host：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. Also available without azide. See T5300-02A.
Specificity：Recognizes human Thyroglobulin. Species crossreactivity: bovine
