85-7204-39 Thrombin 100ug T5045
特徴
- Thrombin is a key clot promoter.
- It is an enzyme that presides over the conversion of a fibrinogen to fibrin.
- The coagulation cascade, is a series of proenzyme-enzyme conversions.
- Coagulation starts when a vessel is wounded.
- A vessel is wrapped in a layer that is full of cells containing Tissue Factor (TF).
- After injury, TF is exposed to blood, it binds with factor VIIa to form the first enzyme: TF:VIIa.
- This activates factor X to Xa, which in turn forms thrombin.
- Applications:Suitable for use in ELISA.
- Not suitable for Western Blot.
- Reported to be suitable for IHC.
- Other applications have not been tested.
- Recommended Dilutions:Optimal dilutions to be determined by the researcher.
- Extinction Coefficient (1cm, 280nm): 14.0
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- Host:mouse
- Source Antibody:human
- Grade:Highly Purified
- Purity:≥95% (SDS-PAGE)
- Form:Supplied as a liquid containing 50% glycerol/50% water (vol/vol).
- Specificity:Recognizes human thrombin kd 1.4x10e-8M, thrombin-ATIII complex kd 1.5x10e-8M, thrombin-FPRcK. Inhibits clotting but not amidase activity. MW: 150kD
- Clone # USB:8.H.10
- Isotype:IgG1
- Calc Applications Abbrev:E
- Calc Crossreactivity:Hu
- Immunogen:Purified human Thrombin
- Shelf Life:1year
- EU Commodity Code:30021010
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