Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas.
In humans, proinsulin is encoded by the INS gene.
Proinsulin is synthesized in the endoplasmic reticulum, where it is folded and its disulfide bonds are oxidized.
It is then transported to the Golgi apparatus where it is packaged into secretory vesicles, and where it is processed by a series of proteases to form mature insulin.
Applications:Suitable for use in ELISA and Immunohistochemistry.
This clone is recommended for use as the solid phase.
Other applications not tested.
Recommended Dilution:To be determined by the researcher.
Affinity Constant:~7.0x10e9
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：1mg
Host：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity：Recognizes the C-Peptide of the beta chain of human Proinsulin. No crossreactivity to Insulin.
