Hemoglobin is composed of one globin plus four hemes; heme consists of protoporphyrin IX and ferrous iron.
The iron content of human hemoglobin is 0.338% which gives a minimal molecular weight of 16,520; however, ultracentrifugal and osmotic pressure measurements indicate an actual molecular weight four times the minimum molecular weight.
Hemoglobin A1C, also known as glycated hemoglobin or glycosylated hemoglobin, indicates a patient's blood sugar control over the last 2-3 months.
A1C is formed when glucose in the blood binds irreversibly to hemoglobin to form a stable glycated hemoglobin complex.
Since the normal life span of red blood cells is 90-120 days, the A1C will only be eliminated when the red cells are replaced; A1C values are directly proportional to the concentration of glucose in the blood over the full life span of the red blood cells.
Applications:Suitable for use in ELISA.
Other applications have not been tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Source:Ascites
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:mouse
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in 0.05M TBS, pH 7.2, 0.05% sodium azide.
Specificity:Recognizes human Hemoglobin A1c. Crossreactivity: All variants of A1c and S1c.
Clone # USB:8.F.127A
Isotype:IgG
Calc Applications Abbrev:E
Calc Crossreactivity:Hu
Immunogen:Hemoglobin A1C, N-Terminal of the beta chain.