Factor VIII (FVIII) is an essential blood clotting factor also known as anti-hemophilic factor (AHF).
In humans, Factor VIII is encoded by the F8 gene.
Defects in this gene results in hemophilia A, a well known recessive X-linked coagulation disorder.
Factor VIII participates in blood coagulation; it is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids forms a complex that converts factor X to the activated form Xa.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Titer:ELISA: 1:16,000
Affinity Constant:8.0x10e9 L/mol
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:500ug
Host:mouse
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4. No preservative added.
Specificity:Recognizes an epitope in the N-terminal region of the 83kD light chain of Human Factor Vlllc: 100%. Does not recognize human Factor VIII or Factor related antigens.