CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells.
CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.
CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed.
In humans, the CD5 gene is located on the long arm of chromosome 11.
Applications:Suitable for use in the detection of T cells and classifying cases of Lymphoma.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ug
Host：mouse
Source Antibody：human
Grade：Highly Purified
Purity：Murine ascites purified by column chromatography.
Form：Supplied as a liquid in PBS buffer, pH 7.5, 0.08% sodium azide.
Specificity：Recognizes and is highly reactive with CD5 antigen (MW 67kD).
