Human serum albumin is a single chain polypeptide which composes ~60% of the plasma proteins.
In normal serum ~10% of the albumin is modified by non-enzymatic glycosylation which occurs primarily on lysine residue number 525.
The amount of glycosylated albumin in serum is markedly elevated in diabetes and thus its determination may help in the monitoring of the disease.
Studies also show that glycosylation of the protein alters its properties and this modification causes it to be ingested by endothelial cells in preference to unmodified albumin.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4. No preservative added.
Specificity：Recognizes glycated human albumin. Does not cross-react with other human glycated proteins, such as HbA1c, glycoHbA0 and glycated LDL. Does not react with deglycated human albumin.
