85-6834-63　Atibuclimab Biosimilar - Research Grade 50mg　ICH5016

特徴

• 背景：RUO atibuclimab is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis. It acts as a pattern recognition receptor for bacterial cell wall components in gram-positive and negative bacteria. CD14 antibody action stimulates a pro-inflammatory cytokine cascade often associated with inflammation in sepsis. Atibuclimab neutralization of this antibody results in the inhibition of TNF-a, IL-6 and IL-10, dampening systemic inflammatory responses. Atibuclimab also delays the release of sTNFR(1) and IL-1ra.

仕様

• サイズ：50mg
• ターゲット：CD14
• 交差性：Human
• 精製方法：This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
• 濃度：5mg/ml
• 構成：Sterile, preservative-free, solution in PBS. BSA and Azide free.
• 純度：>95% by SDS-PAGE
• エンドトキシン：≤ 1.0 EU/mg as determined by the LAL method
• 適用：Functional Assays
• データシート：https://ichor.bio/product/Atibuclimab-Biosimilar-Research-Grade-ICH5016?action=genpdf&id=81050
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