85-6830-51 Bulk anti-Human CD195 （CCR5） antibody （HEK/1/85a/7a） [ICH1172] 5mg ICH1172
![Bulk anti-Human CD195 （CCR5） antibody （HEK/1/85a/7a） [ICH1172] 5mg](https://aimg.as-1.co.jp/c/85/6830/51/85682291.jpg)
特徴
- 背景：CCR5 antibody, HEK/1/85a/7a, recognizes C-C chemokine receptor type 5 (CCR5), also known as CD195, CC-CKR-5, CHEMR13, and HIV-1 fusion coreceptor. CCR5 is a 45 kDa seven-transmembrane G-protein-coupled receptor (GPCR). CCR5 is expressed on a subset of memory T cells, macrophages, and immature dendritic cells (DCs) and is upregulated by proinflammatory cytokines. CCR5 binds to inflammatory CC-chemokines, including CCL3 (macrophage inflammatory protein (MIP)-1α), CCL4 (MIP-1β), and RANTES, which increases intracellular calcium levels and results in cytoskeletal rearrangement and chemotactic cell migration. CCR5 is also the coreceptor for HIV-1 following binding of viral gp120 to CD44-7. The levels of CCR5 on cells influence the rate of entry of HIV-1, and patients with lower levels of CCR5 exhibit immunity against infection. CCR5 also contributes to other human diseases, including type I diabetes and cancer.
仕様
- サイズ：5mg
- ターゲット：CD195
- クローン：HEK/1/85a/7a
- 免疫動物：Rat
- 交差性：Human
- 精製方法：This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- 抗原：CHO cells transfected with full-length human CD195 (CCR5).
- 濃度：≥ 5.0 mg/ml
- 構成：This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
- 純度：≥95% monomer by analytical SEC⋅>95% by SDS Page
- エンドトキシン：<1.0 EU/mg as determined by the LAL method
- Aggregation：Aggregation level ≤ 5%
- 適用：Flow Cytometry, ImmunoCytochemistry
- データシート：https://ichor.bio/product/bulk-anti-human-cd195-ccr5-antibody-hek-1-85a-7a/?action=genpdf&id=79122
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|