85-6829-41 Bulk anti-Human CD38 antibody （OKT10） [ICH1157] 100mg ICH1157
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特徴
- 背景：CD38 is a 45kD type II transmembrane glycoprotein that plays a role in the regulation of intracellular Ca2+ by synthesizing and hydrolyzing an intracellular calcium ion mobilizing messenger. CD38 has both extracellular and intracellular functions as indicated by the release of soluble protein and the ability of membrane-bound protein to become internalized. The functional molecule is a dimer that contains the catalytic site in the central portion, and is involved in both extracellular and intracellular functions. CD38 plays a role in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a biomarker to measure the progress of a chronic lymphocytic leukemia in patients. Because CD38 is expressed on mature lymphocytes and lymphoplasmacytic cells, OKT10 can be used to study final B cell maturation. OKT10 reactivity with CD38 occurs in an inversely proportional relationship to the occurrence of Ia-like antigenic expression. Hence, these two antigens can be used as reciprocal complementary reactants for the study of mature B cell malignancies, such as CLL, multiple myeloma, and Waldenström malignancy.
仕様
- サイズ：100mg
- ターゲット：CD38
- クローン：OKT10
- 免疫動物：Mouse
- 交差性：Human
- 精製方法：This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- 濃度：1mg/ml
- 構成：This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
- 純度：>95% by SDS-PAGE and HPLC
- エンドトキシン：≤ 1.0 EU/mg as determined by the LAL method
- Aggregation：Aggregation level ≤ 5%
- 適用：Flow cytometry
- データシート：https://www.ichor.bio/product/anti-human-cd38-in-vivo-antibody-low-endotoxin-okt10-ich1157/?action=genpdf&id=77045
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- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
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- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6829-38
Bulk anti-Human CD38 antibody （OKT10） [ICH1157] 5mg
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85-6829-41
Bulk anti-Human CD38 antibody （OKT10） [ICH1157] 100mg
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85-6829-40
Bulk anti-Human CD38 antibody （OKT10） [ICH1157] 50mg
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85-6829-39
Bulk anti-Human CD38 antibody （OKT10） [ICH1157] 25mg
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