85-6829-07 Anti-Mouse TCR beta In Vivo Antibody – Low Endotoxin （H57-597） [ICH1153] 25mg ICH1153
![Anti-Mouse TCR beta In Vivo Antibody – Low Endotoxin （H57-597） [ICH1153] 25mg](https://aimg.as-1.co.jp/c/85/6829/07/85682291.jpg)
特徴
- 背景：TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival.
仕様
- サイズ：25mg
- ターゲット：TCR Beta
- クローン：H57-597
- 免疫動物：Armenian Hamster
- 交差性：Mouse
- 精製方法：This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- 抗原：Affinity purified TCR from mouse DO-11.10 cells
- 濃度：≥ 5.0 mg/ml
- 構成：This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
- 純度：≥95% monomer by analytical SEC, >95% by SDS Page
- エンドトキシン：<1.0 EU/mg as determined by the LAL method
- Aggregation：Aggregation level ≤ 5%
- 適用：Flow Cytometry, Costimulatory, Depletion, Immunoprecipitation, IHC (Frozen), IHC (Paraffin), CODEX
- データシート：https://ichor.bio/product/anti-mouse-tcr-beta-in-vivo-antibody-low-endotoxin-h57-597-ich1153/?action=genpdf&id=84886
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