85-6828-71 Anti-Mouse TNF alpha In Vivo Antibody - Ultra Low Endotoxin （TN3-19.12 ） 50mg ICH1136UL
特徴
- 背景：The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity. It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites. TNF-alpha is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-alpha secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-alpha has been detected in synovial fluid of patients with rheumatoid arthritis. Clone TN3-19.12 antibody can neutralize the bioactivity of natural or recombinant TNF-alpha
仕様
- サイズ：50mg
- ターゲット：TNF alpha
- クローン：TN3-19.12
- 免疫動物：Armenian Hamster
- 交差性：Mouse
- 精製方法：This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- 抗原：Recombinant mouse TNFalpha
- 濃度：≥ 2.0 mg/ml
- 構成：0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- 純度：>98% by SDS-PAGE and HPLC
- エンドトキシン：≤ 0.75 EU/mg as determined by the LAL method
- Aggregation：Aggregation level ≤ 1%
- 適用：Immunoprecipitation, Western Blot, Functional Assays, Flow Cytometry, Blocking
- データシート：https://www.ichor.bio/product/Anti-TNF-alpha-In-Vivo-Antibody-Low-Endotoxin-TN3-19.12--ICH1136?action=genpdf&id=69809
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