85-6828-45 Anti-Mouse PD-1 In Vivo Antibody - Ultra Low Endotoxin （RMP1-14） 5mg ICH1132UL
特徴
- 背景：CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
仕様
- サイズ：5mg
- ターゲット：PD-1
- クローン：RMP1-14
- 免疫動物：Rat
- 交差性：Mouse
- 精製方法：This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- 抗原：Mouse PD-1 transfected BHK cells
- 濃度：≥ 2.0 mg/ml
- 構成：0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- 純度：>98% by SDS-PAGE and HPLC
- エンドトキシン：≤ 0.75 EU/mg as determined by the LAL method
- Aggregation：Aggregation level ≤ 1%
- 適用：Western Blot, Blocking, Flow Cytometry, Functional Assays
- データシート：https://www.ichor.bio/product/Anti-PD-1-In-Vivo-Antibody-Low-Endotoxin-RMP1-14-ICH1132?action=genpdf&id=69591
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