85-6828-07　Anti-Mouse IFN beta In Vivo Antibody - Low Endotoxin （MIB-5E9.1） 50mg　ICH1124

特徴

• 背景：Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-alpha proteins and a single IFN-beta protein. The second class, type II IFN, consists of a single protein, IFN-gamma. IFN-alpha and IFN-beta signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-beta has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-beta’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.

仕様

• サイズ：50mg
• ターゲット：IFN beta
• クローン：MIB-5E9.1
• 免疫動物：Armenian Hamster
• 交差性：Mouse
• 精製方法：This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
• 濃度：1.0 mg/ml
• 構成：0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
• 純度：>95% by SDS-PAGE and HPLC
• エンドトキシン：≤ 1.0 EU/mg as determined by the LAL method
• Aggregation：Aggregation level ≤ 5%
• 適用：Western Blot, Blocking
• データシート：https://www.ichor.bio/product/Anti-IFN-beta-In-Vivo-Antibody-Low-Endotoxin-MIB-5E9.1-ICH1124?action=genpdf&id=69348
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