85-6827-99 Anti-Mouse IFNAR1 In Vivo Antibody - Low Endotoxin (MAR1-5A3) 100mg ICH1122
特徴
- 背景:The antibody when prepared specifically for In vivo functional assays blocks type I IFN receptor signaling both In vitro and In vivo without depleting IFNAR1 bearing cells. This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmid encoding the extracellular domain of murine IFNAR1. IFNAR1 and IFNAR2 are coexpressed on nearly all cells and make up the heterodimeric receptor that binds all type I IFNs (IFN alpha and beta). Type I IFNs are a family of cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor and autoimmune responses In vivo.
仕様
- サイズ:100mg
- ターゲット:IFNAR1
- クローン:MAR1-5A3
- 免疫動物:Mouse
- 交差性:Mouse
- 抗原:This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmid encoding the extracellular domain of murine IFNAR1.
- 濃度:≥ 2.0 mg/ml
- 構成:0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- 純度:>95% by SDS-PAGE and HPLC
- エンドトキシン:≤ 1.0 EU/mg as determined by the LAL method
- Aggregation:Aggregation level ≤ 5%
- 適用:Immunoprecipitation, Western Blot, Blocking, Functional Assays, Flow Cytometry, ELISA
- データシート:https://www.ichor.bio/product/Anti-IFNAR1-In-Vivo-Antibody-Low-Endotoxin-MAR1-5A3-ICH1122?action=genpdf&id=69231
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