85-6827-95 Anti-Mouse IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) 100mg ICH1117
特徴
- 背景:IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1alpha and IL-1beta exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1alpha and IL-1beta, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
仕様
- サイズ:100mg
- ターゲット:IL1R1
- クローン:JAMA-147
- 免疫動物:Armenian Hamster
- 交差性:Mouse
- 精製方法:This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- 抗原:Extracellular domain of mouse IL-1 R type 1
- 濃度:1.0 - 5.0 mg/ml
- 構成:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- 純度:>95% by SDS-PAGE and HPLC
- エンドトキシン:≤ 1.0 EU/mg as determined by the LAL method
- Aggregation:Aggregation level ≤ 5%
- 適用:Immunoprecipitation, Western Blot, Blocking, Flow Cytometry
- データシート:https://www.ichor.bio/product/Anti-IL-1R-In-Vivo-Antibody-Low-Endotoxin-JAMA-147-ICH1117?action=genpdf&id=69301
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6827-93
Anti-Mouse IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) 25mg
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85-6827-92
Anti-Mouse IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) 5mg
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85-6827-95
Anti-Mouse IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) 100mg
|
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85-6827-94
Anti-Mouse IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) 50mg
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