85-6827-76 Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin （IK22/5） 5mg ICH1114
特徴
- 背景：RANKL (Receptor Activator for Nuclear Factor κ B Ligand), also known as TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and ODF (osteoclast differentiation factor), is a member of the tumor necrosis factor family cytokine. RANKL is essential for osteoclast formation, activation, and survival. RANKL through interaction with its receptor RANK can modulate matrix degradation and inflammation. RANKL and RANK have essential roles in lymph node formation, establishment of the thymic microenvironment, and development of a lactating mammary gland during pregnancy. Consequently, novel drugs specifically targeting RANK, RANKL, and their signaling pathways in osteoclasts are expected to revolutionize the treatment of various ailments associated with bone loss, such as arthritis, periodontal disease, cancer metastases, and osteoporosis.
仕様
- サイズ：5mg
- ターゲット：RANKL
- クローン：IK22/5
- 免疫動物：Rat
- 交差性：Mouse
- 精製方法：This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- 抗原：Purified Recombinant Mouse RANKL (NSO-derived)
- 濃度：1.0 mg/ml
- 構成：0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- 純度：>95% by SDS-PAGE and HPLC
- エンドトキシン：<0.5 EU/mg as determined by the LAL method
- Aggregation：Aggregation level ≤ 5%
- 適用：Flow Cytometry, Immunoprecipitation, Western Blot, Blocking, Immunofluorescence, IHC (Frozen)
- データシート：https://www.ichor.bio/product/anti-rankl-in-vivo-antibody-low-endotoxin-ik22-5-ich1114/?action=genpdf&id=69724
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6827-76
Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin （IK22/5） 5mg
|
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85-6827-78
Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin （IK22/5） 50mg
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85-6827-77
Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin （IK22/5） 25mg
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85-6827-79
Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin （IK22/5） 100mg
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