85-6826-69 Anti-Mouse CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (UC10-4F10-11) 50mg ICH1085UL
特徴
- 背景:CD152, also known as CTLA-4 or Ly-56 has significant similarity to CD28 in amino acid sequence, structure, and genomic organization. Furthermore, CD152 and CD28 share common B7 family counter-receptors. Unlike CD28, CD152 expression appears to be restricted to activated T cells and CD25+CD4+ regulatory T (Treg) cells. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation.
仕様
- サイズ:50mg
- ターゲット:CTLA-4
- クローン:UC10-4F10-11
- 免疫動物:Armenian Hamster
- 交差性:Mouse
- 精製方法:This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- 抗原:Purified Recombinant Mouse CTLA4 Fc Fusion Protein
- 濃度:≥ 2.0 mg/ml
- 構成:0.01 M phosphate buffered saline (PBS) pH 7.4, without BSA or sodium azide added.
- 純度:>98% by SDS-PAGE and HPLC
- エンドトキシン:≤ 0.75 EU/mg as determined by the LAL method
- Aggregation:Aggregation level ≤ 1%
- 適用:Flow Cytometry, Western Blot, Functional Assays, Immunoprecipitation
- データシート:https://www.ichor.bio/product/Anti-CTLA-4-In-Vivo-Antibody-Low-Endotoxin-UC10-4F10-11-ICH1085?action=genpdf&id=66803
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