85-6826-01　Anti-Mouse CD115 In Vivo Antibody - Low Endotoxin （AFS98） 50mg　ICH1068

特徴

• 背景：Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.

仕様

• サイズ：50mg
• ターゲット：CD115
• クローン：AFS98
• 免疫動物：Rat
• 交差性：Mouse
• 精製方法：This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
• 抗原：Purified Recombinant Mouse M-CSFR
• 濃度：1.0 - 5.0 mg/ml
• 構成：0.01 M phosphate buffered saline (PBS), pH 7.2 - 7.4 without azide or BSA.
• 純度：>95% by SDS-PAGE and HPLC
• エンドトキシン：≤ 1.0 EU/mg as determined by the LAL method
• Aggregation：Aggregation level ≤ 5%
• 適用：Western Blot, Blocking, Functional Assays, Flow Cytometry
• データシート：https://www.ichor.bio/product/Anti-CD115-In-Vivo-Antibody-Low-Endotoxin-AFS98-ICH1068?action=genpdf&id=66119
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