85-6656-25　Phospho-CAD （T456） Polyclonal Antibody 20ul　BT-PHS01083

特徴

• 背景：The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human CAD around the phosphorylation site of Thr456. AA range:422-471
• 免疫動物：Rabbit
• 交差性：Human;mouse
• 適用：IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：CAD; CAD protein
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