85-6656-06　Phospho-Bcl-x （T115） Polyclonal Antibody 100ul　BT-PHS01069

特徴

• 背景：The protein encoded by BCL2L1 (BCL2 like 1) belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.

仕様

• サイズ：100ul
• 抗原：The antiserum was produced against synthesized peptide derived from human BCL-XL around the phosphorylation site of Thr115. AA range:81-130
• 免疫動物：Rabbit
• 交差性：Human;mouse;rat
• 適用：IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：BCL2L1; BCL2L; BCLX; Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X
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