85-6655-55　Phospho-Adducin Alpha （T445） Polyclonal Antibody 20ul　BT-PHS00955

特徴

• 背景：Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human ADD1 around the phosphorylation site of Thr445. AA range:411-460
• 免疫動物：Rabbit
• 交差性：Human;mouse;rat
• 適用：IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：ADD1; ADDA; Alpha-adducin; Erythrocyte adducin subunit alpha
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