85-6653-76　Phospho-ACC Alpha （S80） Polyclonal Antibody 20ul　BT-PHS00595

特徴

• 背景：Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for ACACA.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human ACC1 around the phosphorylation site of Ser80. AA range:46-95
• 免疫動物：Rabbit
• 交差性：Human;mouse;rat
• 適用：WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：ACACA; ACAC; ACC1; ACCA; Acetyl-CoA carboxylase 1; ACC1; ACC-alpha
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