85-6650-03　uMtCK Monoclonal Antibody 100ul　BT-MCA1268

特徴

• 背景：Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mi

仕様

• サイズ：100ul
• 抗原：Purified recombinant human uMtCK protein fragments expressed in E.coli.
• 免疫動物：Mouse
• 交差性：Human,Mouse,Rat,Dog,Pig,Rabbit
• 適用：WB
• クラス：IgG
• クロナリティ：Monoclonal
• 濃度：1 mg/ml
• 別名：CKMT1A; CKMT; CKMT1B; CKMT; Creatine kinase U-type; mitochondrial; Acidic-type mitochondrial creatine kinase; Mia-CK; Ubiquitous mitochondrial creatine kinase; U-MtCK
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