85-6646-49 RAG-2 Monoclonal Antibody 100ul BT-MCA1090
特徴
- 背景：This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodef
仕様
- サイズ：100ul
- 抗原：Purified recombinant fragment of human RAG-2 (350-527aa) expressed in E. Coli.
- 免疫動物：Mouse
- 交差性：Human
- 適用：WB, ELISA
- クラス：IgG
- クロナリティ：Monoclonal
- 濃度：1 mg/ml
- 別名：RAG2; V(D)J recombination-activating protein 2; RAG-2
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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85-6646-49
RAG-2 Monoclonal Antibody 100ul
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85-6646-48
RAG-2 Monoclonal Antibody 50ul
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