85-6646-06　PRMT6 Monoclonal Antibody 50ul　BT-MCA1066

特徴

• 背景：The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

仕様

• サイズ：50ul
• 抗原：Purified recombinant human PRMT6 protein fragments expressed in E.coli.
• 免疫動物：Mouse
• 交差性：Human,Mouse,Rat
• 適用：WB, IHC-p, IF, ICC
• クラス：IgG
• クロナリティ：Monoclonal
• 濃度：1 mg/ml
• 別名：PRMT6; HRMT1L6; Protein arginine N-methyltransferase 6; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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