85-6644-99　PDH-E1 Alpha Monoclonal Antibody 100ul　BT-MCA1012

特徴

• 背景：The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

仕様

• サイズ：100ul
• 抗原：Purified recombinant human PDH-E1α (C-terminus) protein fragments expressed in E.coli.
• 免疫動物：Mouse
• 交差性：Human,Mouse,Rat,Bovine,Dog,Pig
• 適用：WB, IF, ICC
• クラス：IgG
• クロナリティ：Monoclonal
• 濃度：1 mg/ml
• 別名：PDHA1; PHE1A; Pyruvate dehydrogenase E1 component subunit alpha; somatic form, mitochondrial; PDHE1-A type I
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