85-6644-65　PA28 Gamma Monoclonal Antibody 50ul　BT-MCA0983

特徴

• 背景：The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) o

仕様

• サイズ：50ul
• 抗原：Purified recombinant human PA28γ protein fragments expressed in E.coli.
• 免疫動物：Mouse
• 交差性：Human,Mouse,Dog,Pig
• 適用：WB, IF, ICC
• クラス：IgG
• クロナリティ：Monoclonal
• 濃度：1 mg/ml
• 別名：PSME3; Proteasome activator complex subunit 3; 11S regulator complex subunit gamma; REG-gamma; Activator of multicatalytic protease subunit 3; Ki nuclear autoantigen; Proteasome activator 28 subunit gamma; PA28g; PA28gamma
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