85-6636-80 ER81 Monoclonal Antibody 50ul BT-MCA0501
特徴
- 背景：This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alte
仕様
- サイズ：50ul
- 抗原：Purified recombinant fragment of ER81 (aa1-191) expressed in E. Coli.
- 免疫動物：Mouse
- 交差性：Human
- 適用：WB, ELISA
- クラス：IgG
- クロナリティ：Monoclonal
- 濃度：1 mg/ml
- 別名：ETV1; ER81; ETS translocation variant 1; Ets-related protein 81
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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85-6636-80
ER81 Monoclonal Antibody 50ul
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85-6636-81
ER81 Monoclonal Antibody 100ul
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