85-6635-64　DDR2 Monoclonal Antibody 50ul　BT-MCA0439

特徴

• 背景：Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcr

仕様

• サイズ：50ul
• 抗原：Purified recombinant fragment of human DDR2 expressed in E. Coli.
• 免疫動物：Mouse
• 交差性：Human
• 適用：WB, IHC-p, IF, ICC, ELISA
• クラス：IgG
• クロナリティ：Monoclonal
• 濃度：1 mg/ml
• 別名：DDR2; NTRKR3; TKT; TYRO10; Discoidin domain-containing receptor 2; Discoidin domain receptor 2; CD167 antigen-like family member B; Discoidin domain-containing receptor tyrosine kinase 2; Neurotrophic tyrosine kinase; receptor-related 3; Re
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