85-6632-08　BPTF Monoclonal Antibody 50ul　BT-MCA0232

特徴

• 背景：This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome

仕様

• サイズ：50ul
• 抗原：Purified recombinant fragment of human BPTF expressed in E. Coli.
• 免疫動物：Mouse
• 交差性：Human
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Monoclonal
• 濃度：1 mg/ml
• 別名：BPTF; FAC1; FALZ; Nucleosome-remodeling factor subunit BPTF; Bromodomain and PHD finger-containing transcription factor; Fetal Alz-50 clone 1 protein; Fetal Alzheimer antigen
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